Inhibitory effects of Syzygium jambos extract on biomarkers of endothelial cell activation.

ABSTRACT:

Background

Disordered endothelial cell activation plays an important role in the pathophysiology of atherosclerosis, cancer, sepsis, viral infections, and inflammatory responses. There is interest in developing novel therapeutics to regulate endothelial cell function in atherothrombotic, metabolic, vascular, and hematological diseases. Extracts from leaves of the Syzygium jambos (L.) Alston (S. jambos) trees have been proposed to treat cardiovascular diseases and diabetes through unclear mechanisms. We investigated the effects of the S. jambos extract on biomarkers of endothelial dysfunction and immune responses in the human endothelial cell line, EA.hy926.

Methods

Leaves of S. jambos were collected, concocted and lyophilized. To study the effects of S. jambos on endothelial

SUBMITTER: Inostroza-Nieves Y 

PROVIDER: S-EPMC8988540 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature