A lower psoas muscle index predicts a poorer prognosis in metastatic hormone-naive prostate cancer.

ABSTRACT:

Introduction

A recent investigation revealed that sarcopenia was associated with a poorer prognosis in some solid malignancies, including prostate cancer. In most reports, sarcopenia was defined as a low psoas volume on CT. This study investigated the association of sarcopenia, determined according to the psoas muscle volume and density on CT, with the prognosis in patients with metastatic hormone-naïve prostate cancer (mHNPC).

Methods

A total of 66 patients initially diagnosed with mHNPC were enrolled in this study. Skeletal muscle was evaluated according to the psoas muscle index density (PMID) on computed tomography scans. The psoas muscle volume was calculated at the level of L3 and CT density was evaluated as the mean CT density at the psoas muscle area. We divided the

SUBMITTER: Iwamoto G 

PROVIDER: S-EPMC8988845 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature