Medical interventions for chronic rhinosinusitis in cystic fibrosis.

ABSTRACT:

Background

Chronic rhinosinusitis frequently occurs in people with cystic fibrosis. Several medical interventions are available for treating chronic rhinosinusitis in people with cystic fibrosis; for example, different concentrations of nasal saline irrigations, topical or oral corticosteroids, antibiotics - including nebulized antibiotics - dornase alfa and modulators of the cystic fibrosis transmembrane conductance regulator (CFTR) (such as lumacaftor, ivacaftor or tezacaftor). However, the efficacy of these interventions is unclear. This is an update of a previously published review.

Objectives

The objective of this review is to compare the effects of different medical interventions in people diagnosed with cystic fibrosis and chronic rhinosinusitis.

Search methods

SUBMITTER: Karanth TK 

PROVIDER: S-EPMC8989145 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature