Association of weight change following smoking cessation with the risk of tuberculosis development: A nationwide population-based cohort study.

ABSTRACT:

Background

Smoking or weight loss is a risk of tuberculosis (TB) development. However, the impact of weight change after smoking cessation on the occurrence of TB remains elusive. We aimed to determine the relationship between weight change after smoking cessation and the risk of TB development.

Methods

We conducted a population-based cohort study using the national database in Republic of Korea. Of the 10,490,491 subjects who underwent health check-up in 2009, we enrolled 9,953,124 subjects without a previous TB history and followed them until 2017. We divided all study participants into the following three groups: never, former, and current smokers. The primary endpoint was newly developed TB.

Results

Among 9,953,124 subjects analyzed, 5,922,845 (59.5%) were never s

SUBMITTER: Kim SH 

PROVIDER: S-EPMC8989195 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature