Novel Approaches for the Treatment of Patients with Richter's Syndrome.

ABSTRACT:

Opinion statement

In the last 10-15 years, the way to treat cancers has dramatically changed towards precision medicine approaches. These treatment options are mainly based on selective targeting against signaling pathways critical for or detrimentally activated in cancer cells in cancer cells, as well as exploiting molecules that are specifically expressed on neoplastic cells, also known as tumor-associated antigens. These considerations hold true also in the hematological field where a plethora of novel targeted agents have reached patients' bedside, significantly improving clinical responses. Chronic lymphocytic leukemia (CLL) is an example of how targeted therapies, such as BTK, PI3K, or Bcl-2 inhibitors as well as anti-CD20 antibodies, have improved patients' management, even

SUBMITTER: Iannello A 

PROVIDER: S-EPMC8989931 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature