Longitudinal Associations Between Maternal Glucose Levels and Ultrasonographic Fetal Biometrics in a Shanghai Cohort.

ABSTRACT:

Importance

Evidence on the timing of fetal growth alterations associated with gestational diabetes or on the association of the maternal glycemic trajectory with fetal growth during pregnancy remains lacking.

Objective

To examine the associations between maternal glucose levels and offspring intrauterine growth.

Design, setting, and participants

This cohort study used data from 4574 eligible pregnant women and their offspring in the Shanghai Maternal-Child Pairs Cohort collected from April 10, 2016, to April 30, 2018. Group-based trajectory modeling was used to classify fasting plasma glucose levels during pregnancy into 3 glycemic trajectories (trajectory 1, consistently normal glucose levels in all 3 trimesters; trajectory 2, hyperglycemia only in late pregnancy; an

SUBMITTER: Zou JJ 

PROVIDER: S-EPMC8990351 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature