Cerebral venous sinus thrombosis in the setting of COVID-19 vaccination: a systematic review and meta-analysis.

ABSTRACT:

Background and purpose

Cerebral venous sinus thrombosis (CVST) has been reported as a rare adverse event in association with thrombosis-thrombocytopenia syndrome (TTS) following COVID-19 vaccination.

Methods

 We performed a systematic review and meta-analysis of investigator-initiated registries including confirmed CVST cases, with the aim to calculate (1) the odds ratio of TTS-CVST versus non-TTS-CVST after vector-based vaccines and (2) after non-vector-based vaccines, (3) the in-hospital mortality ratio of TTS-CVST compared to non-TTS-CVST; and (4) the dependency or death at discharge among TTS-CVST compared to non-TTS-CVST cases.

Results

Two eligible studies were included in the meta-analysis, comprising a total of 211 patients with CVST associated with COVID-19 va

SUBMITTER: Palaiodimou L 

PROVIDER: S-EPMC8990450 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature