Dietary fatty acid metabolism: New insights into the similarities of lipid metabolism in humans and hamsters.

ABSTRACT: Hamsters have been long accepted as animal models to study the lipid metabolism in humans. However, very few scientific works described in detail the fatty acid (FA) composition of plasma and erythrocytes in hamsters in relation to their dietary intake, and none work was found comparing them with that described in humans. Therefore, a study was carried out to compare the effect of ingesting olive oil or dairy fat, as part of an equilibrated diet in healthy subjects, on plasma and erythrocytes FA composition. More than 40 FA were detected in samples of both species. It was demonstrated that plasma total FA (TFA) concentration and FA profiles are similar in humans and hamsters. In both species linoleic, oleic and palmitic acids are the main FA and accounted for the 70% of TFA. Differences fo

SUBMITTER: Berriozabalgoitia A 

PROVIDER: S-EPMC8991696 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature