Autoimmune disease and COVID-19: a multicentre observational study in the United Kingdom.

ABSTRACT:

Objective

To establish the demographic characteristics, laboratory findings and clinical outcomes in patients with autoimmune disease (AD) compared with a propensity-matched cohort of patients without AD admitted with COVID-19 to hospitals in the UK.

Methods

This is a multicentre observational study across 26 NHS Trusts. Data were collected both retrospectively and prospectively using a predesigned standardized case record form. Adult patients (≥18 years) admitted between 1 April 2020 and 31 July 2020 were included.

Results

Overall, 6288 patients were included to the study. Of these, 394 patients had AD prior to admission with COVID-19. Of 394 patients, 80 patients with SLE, RA or aPL syndrome were classified as severe rheumatologic AD. A higher proportion of those wi

SUBMITTER: Arachchillage DJ 

PROVIDER: S-EPMC8992350 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature