Partial COVID-19 vaccination associated with reduction in postoperative mortality and SARS-CoV-2 infection.

ABSTRACT:

Background

There are currently no data to guide decisions about delaying surgery to achieve full vaccination.

Methods

We analyzed data from patients undergoing surgery at any of the 1,283 VA medical facilities nationwide and compared postoperative complication rates by vaccination status.

Results

Of 87,073 surgical patients, 20% were fully vaccinated, 15% partially vaccinated, and 65% unvaccinated. Mortality was reduced in full vaccination vs. unvaccinated (Incidence Rate Ratio 0.77, 95% CI [0.62, 0.94]) and partially vaccinated vs. unvaccinated (0.75 [0.60, 0.94]). Postoperative COVID-19 infection was reduced in fully (0.18 [0.12, 0.26]) and partially vaccinated patients (0.34 [0.24, 0.48]). Fully vaccinated compared to partially vaccinated patients, had similar post

SUBMITTER: Prasad NK 

PROVIDER: S-EPMC8993410 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature