A wastewater-based epidemic model for SARS-CoV-2 with application to three Canadian cities.

ABSTRACT: The COVID-19 pandemic has stimulated wastewater-based surveillance, allowing public health to track the epidemic by monitoring the concentration of the genetic fingerprints of SARS-CoV-2 shed in wastewater by infected individuals. Wastewater-based surveillance for COVID-19 is still in its infancy. In particular, the quantitative link between clinical cases observed through traditional surveillance and the signals from viral concentrations in wastewater is still developing and hampers interpretation of the data and actionable public-health decisions. We present a modelling framework that includes both SARS-CoV-2 transmission at the population level and the fate of SARS-CoV-2 RNA particles in the sewage system after faecal shedding by infected persons in the population. Using our mechanistic

SUBMITTER: Nourbakhsh S 

PROVIDER: S-EPMC8993419 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature