Mathematical modeling of COVID-19 in British Columbia: An age-structured model with time-dependent contact rates.

ABSTRACT: Following the emergence of COVID-19 at the end of 2019, several mathematical models have been developed to study the transmission dynamics of this disease. Many of these models assume homogeneous mixing in the underlying population. However, contact rates and mixing patterns can vary dramatically among individuals depending on their age and activity level. Variation in contact rates among age groups and over time can significantly impact how well a model captures observed trends. To properly model the age-dependent dynamics of COVID-19 and understand the impacts of interventions, it is essential to consider heterogeneity arising from contact rates and mixing patterns. We developed an age-structured model that incorporates time-varying contact rates and population mixing computed from the o

SUBMITTER: Iyaniwura SA 

PROVIDER: S-EPMC8993502 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature