Real-time molecular imaging of near-surface tissue using Raman spectroscopy.

ABSTRACT: The steady progress in medical diagnosis and treatment of diseases largely hinges on the steady development and improvement of modern imaging modalities. Raman spectroscopy has attracted increasing attention for clinical applications as it is label-free, non-invasive, and delivers molecular fingerprinting information of a sample. In combination with fiber optic probes, it also allows easy access to different body parts of a patient. However, image acquisition with fiber optic probes is currently not possible. Here, we introduce a fiber optic probe-based Raman imaging system for the real-time molecular virtual reality data visualization of chemical boundaries on a computer screen and the physical world. The approach is developed around a computer vision-based positional tracking system in c

SUBMITTER: Yang W 

PROVIDER: S-EPMC8993924 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature