The effects of orthobiologics in the treatment of tendon pathologies: a systematic review of preclinical evidence.

ABSTRACT:

Purpose

The aim of this systematic review is to explore the current available knowledge about tendon disorders and orthobiologics derived by preclinical experiments to evaluate their role and efficacy in the different stages and conditions related to the tendon healing processes.

Methods

The systematic review was performed according to the PRISMA guidelines. Different electronic databases (MEDLINE, Web of Science, EMBASE) were searched for studies investigating orthobiologics (PRP and cell-based products from adipose tissue or bone marrow) in animal models or veterinary clinical trials for tendon pathologies (complete/partial tendon ruptures, rotator cuff tears, tendinopathy, enthesis-related injuries). Data regarding the specific product used, the treatment site/pathology,

SUBMITTER: Vigano M 

PROVIDER: S-EPMC8994001 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature