Diagnostic value of circulating genetically abnormal cells to support computed tomography for benign and malignant pulmonary nodules.

ABSTRACT:

Background

The accuracy of CT and tumour markers in screening lung cancer needs to be improved. Computer-aided diagnosis has been reported to effectively improve the diagnostic accuracy of imaging data, and recent studies have shown that circulating genetically abnormal cell (CAC) has the potential to become a novel marker of lung cancer. The purpose of this research is explore new ways of lung cancer screening.

Methods

From May 2020 to April 2021, patients with pulmonary nodules who had received CAC examination within one week before surgery or biopsy at First Affiliated Hospital of Zhengzhou University were enrolled. CAC counts, CT scan images, serum tumour marker (CEA, CYFRA21-1, NSE) levels and demographic characteristics of the patients were collected for analysis. CT w

SUBMITTER: Yang H 

PROVIDER: S-EPMC8994303 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature