The development of theory-informed participant-centred interventions to maximise participant retention in randomised controlled trials.

ABSTRACT:

Background

A failure of clinical trials to retain participants can influence the trial findings and significantly impact the potential of the trial to influence clinical practice. Retention of participants involves people, often the trial participants themselves, performing a behaviour (e.g. returning a questionnaire or attending a follow-up clinic as part of the research). Most existing interventions that aim to improve the retention of trial participants fail to describe any theoretical basis for the potential effect (on behaviour) and also whether there was any patient and/or participant input during development. The aim of this study was to address these two problems by developing theory- informed, participant-centred, interventions to improve trial retention.

Methods

Th

SUBMITTER: Newlands R 

PROVIDER: S-EPMC8994320 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature