Deep transcranial magnetic stimulation in combination with skin thermography in obesity: a window on sympathetic nervous system.

ABSTRACT:

Aims

Obesity is known to be associated with an altered thermoregulation as well as a dysregulation of sympathetic nervous system (SNS). Considering the ability of deep transcranial magnetic stimulation (dTMS) to modulate the SNS, we hypothesized a potential role of dTMS in affecting thermoregulation in obesity. Aims of the study were to monitor the effect of a single session of dTMS on body temperature in subjects with obesity, and to correlate the dTMS-induced changes in body temperature with activation of the SNS (epinephrine and norepinephrine release).

Methods

Twenty-nine subjects with obesity [5 M, 24 F; age 50 (IQR: 58, 38) yrs; BMI 36.1 (IQR: 33.9, 38.7) kg/m²] were randomized into 2 groups receiving a single session of high frequency stimulation (HF) or sh

SUBMITTER: Ferrulli A 

PROVIDER: S-EPMC8995296 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature