The Effects of CPAP Treatment on Resting-State Network Centrality in Obstructive Sleep Apnea Patients.

ABSTRACT:

Background and objectives

Obstructive sleep apnea (OSA) is the most common sleep disorder and previous studies have shown that OSA patients suffer from brain network impairments associated with cognitive deficits, and continuous positive airway pressure (CPAP) treatment can improve clinical symptoms. However, the relationship between CPAP treatment and brain network changes remains unclear. This study explored the characteristics of brain network changes in OSA patients before (pre-CPAP) and after one month of CPAP treatment (post-CPAP).

Methods

We collected data, including sleep monitoring, clinical assessment, and magnetic resonance imaging scans, from 21 OSA patients and 21 age-matched healthy controls (HCs). Voxel-level degree centrality (DC) was used to assess whole-bra

SUBMITTER: Li P 

PROVIDER: S-EPMC8995649 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature