Alteration in the Functional Organization of the Default Mode Network Following Closed Non-severe Traumatic Brain Injury.

ABSTRACT: The debilitating effect of traumatic brain injury (TBI) extends years after the initial injury and hampers the recovery process and quality of life. In this study, we explore the functional reorganization of the default mode network (DMN) of those affected with non-severe TBI. Traumatic brain injury (TBI) is a wide-spectrum disease that has heterogeneous effects on its victims and impacts everyday functioning. The functional disruption of the default mode network (DMN) after TBI has been established, but its link to causal effective connectivity remains to be explored. This study investigated the differences in the DMN between healthy participants and mild and moderate TBI, in terms of functional and effective connectivity using resting-state functional magnetic resonance imaging (fMRI). N

SUBMITTER: Abdul Rahman MR 

PROVIDER: S-EPMC8995774 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature