Altered Brain Criticality in Schizophrenia: New Insights From Magnetoencephalography.

ABSTRACT: Schizophrenia has a complex etiology and symptomatology that is difficult to untangle. After decades of research, important advancements toward a central biomarker are still lacking. One of the missing pieces is a better understanding of how non-linear neural dynamics are altered in this patient population. In this study, the resting-state neuromagnetic signals of schizophrenia patients and healthy controls were analyzed in the framework of criticality. When biological systems like the brain are in a state of criticality, they are thought to be functioning at maximum efficiency (e.g., optimal communication and storage of information) and with maximum adaptability to incoming information. Here, we assessed the self-similarity and multifractality of resting-state brain signals recorded with

SUBMITTER: Alamian G 

PROVIDER: S-EPMC8995790 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature