Neuromodulation Enables Temperature Robustness and Coupling Between Fast and Slow Oscillator Circuits.

ABSTRACT: Acute temperature changes can disrupt neuronal activity and coordination with severe consequences for animal behavior and survival. Nonetheless, two rhythmic neuronal circuits in the crustacean stomatogastric ganglion (STG) and their coordination are maintained across a broad temperature range. However, it remains unclear how this temperature robustness is achieved. Here, we dissociate temperature effects on the rhythm generating circuits from those on upstream ganglia. We demonstrate that heat-activated factors extrinsic to the rhythm generators are essential to the slow gastric mill rhythm's temperature robustness and contribute to the temperature response of the fast pyloric rhythm. The gastric mill rhythm crashed when its rhythm generator in the STG was heated. It was restored when ups

SUBMITTER: Stadele C 

PROVIDER: S-EPMC8996074 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature