Integrated Transcriptome Analysis of Iris Tissues in Experimental Autoimmune Uveitis.
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ABSTRACT:
SUBMITTER: Li D
PROVIDER: S-EPMC8996140 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Integrated Transcriptome Analysis of Iris Tissues in Experimental Autoimmune Uveitis.
Li Dan D Huang Chang C Han Xiaoyan X Sun Jianguo J
Frontiers in genetics 20220328
Uveitis is a severe ocular inflammatory disease that affects the uvea and frequently results in visual impairment, even irreversible blindness. The current treatments for uveitis have exhibited adverse side effects. To find novel targets of this disease, we perform comparative transcriptome analysis using normal (<i>n</i> = 4) and experimental autoimmune uveitis (EAU) (<i>n</i> = 4) rat iris samples. We mainly focus on the expression profiles of mRNAs and long non-coding RNAs, and identify NOD-l ...[more]
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