Dipolar Relaxation of Water Protons in the Vicinity of a Collagen-like Peptide.

ABSTRACT: Quantitative magnetic resonance imaging is one of the few available methods for noninvasive diagnosis of degenerative changes in articular cartilage. The clinical use of the imaging data is limited by the lack of a clear association between structural changes at the molecular level and the measured magnetic relaxation times. In anisotropic, collagen-containing tissues, such as articular cartilage, the orientation dependency of nuclear magnetic relaxation can obscure the content of the images. Conversely, if the molecular origin of the phenomenon would be better understood, it would provide opportunities for diagnostics as well as treatment planning of degenerative changes in these tissues. We study the magnitude and orientation dependence of the nuclear magnetic relaxation due to dipole-di

SUBMITTER: Karjalainen J 

PROVIDER: S-EPMC8996236 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature