Association of High Dietary Acid Load With the Risk of Cancer: A Systematic Review and Meta-Analysis of Observational Studies.

ABSTRACT:

Objective

This study aimed to determine the relationship between the high dietary acid load (DAL) and the risk of cancer.

Methods

Five databases of PubMed, Web of Sciences, Scopus, Cochrane Library, and Google Scholar was searched to elicit original studies on humans, up to June 2021. Quality of the articles, risk of bias, and heterogeneity were assessed. A random-effects meta-analysis model was applied to estimate pooled effect size with a 95% confidence interval. Sensitivity analysis was performed using a fixed-effects model. Subgroup analyses were carried out based on gender, age, type of cancer, and type of DAL assessment indicator.

Results

Seventeen effect sizes from 10 articles were included in the analysis. Overall, individuals with the highest DAL were associa

SUBMITTER: Keramati M 

PROVIDER: S-EPMC8997294 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature