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Clinical characteristics and prognostic factors of fibrotic nonspecific interstitial pneumonia.


ABSTRACT:

Aim

Several studies have reported favorable outcomes of nonspecific interstitial pneumonia (NSIP); however, its prognosis and prognostic factors remain unclear. This study aimed to determine the outcomes of fibrotic NSIP and the prognostic factors for progression, relapse, and survival.

Methods

In this retrospective study, we reviewed the clinical data of 204 patients diagnosed with fibrotic NSIP by surgical lung biopsy at Samsung Medical Center. The factors associated with survival and disease progression or relapse were determined using Cox proportional hazard analysis.

Results

The median age of patients was 54 years and 67 (33%) patients were male. Also, 47 patients (23%) were current or ex-smokers. In all, 141 (69%) patients were diagnosed with idiopathic NSIP, wh

SUBMITTER: Cho HK 

PROVIDER: S-EPMC8998371 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature