The Therapeutic Potential of Exosomes in Soft Tissue Repair and Regeneration.

ABSTRACT: Soft tissue defects are common following trauma and tumor extirpation. These injuries can result in poor functional recovery and lead to a diminished quality of life. The healing of skin and muscle is a complex process that, at present, leads to incomplete recovery and scarring. Regenerative medicine may offer the opportunity to improve the healing process and functional outcomes. Barriers to regenerative strategies have included cost, regulatory hurdles, and the need for cell-based therapies. In recent years, exosomes, or extracellular vesicles, have gained tremendous attention in the field of soft tissue repair and regeneration. These nanosized extracellular particles (30-140 nm) can break the cellular boundaries, as well as facilitate intracellular signal delivery in various regenerativ

SUBMITTER: Wan R 

PROVIDER: S-EPMC8998690 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature