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Low Five-Minute Apgar Score and Neurological Morbidities: Does Prematurity Modify the Association?


ABSTRACT: (1) Background: We aimed to study whether a low 5 min Apgar score is associated with pediatric neurological morbidities throughout childhood. (2) Methods: A population-based retrospective cohort study was conducted. The exposed group was defined as offspring with a 5 min Apgar score <7, and the remaining offspring served as the comparison group. The primary outcome was defined as pediatric hospitalizations with any neurological morbidity. Multivariable survival models were used to evaluate the association between the exposure and outcome while adjusting for potential confounders. Additional models were used to study this association separately among term- and preterm-born offspring. (3) Results: The study population included 349,385 singletons born between the years 1991 and 2021, 0.6%

SUBMITTER: Wainstock T 

PROVIDER: S-EPMC8999413 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature