Risk Stratification and Clinical Characteristics of Patients with Late Recurrence of Melanoma (>10 Years).

ABSTRACT:

Background

Most patients with high-risk melanomas develop metastasis within the first few years after diagnosis. However, late recurrence of melanoma is seen in patients that metastasize more than 10 years after the primary diagnosis; a metastasis after 15 years is considered an ultra-late recurrence. It is critical to better understand the clinical and biological characteristics of this subset of melanoma patients in order to offer an individual treatment plan and prevent metastasis.

Methods

We retrospectively analyzed melanoma patients with recurrence ≥10 years after a primary diagnosis documented between 1993 and 2012 at the skin cancer center of the University Medical Center Leipzig, Germany. We conducted a comprehensive review of the literature and compared the results

SUBMITTER: Reschke R 

PROVIDER: S-EPMC9000041 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature