Mortality rates among COVID-19 patients hospitalised during the first three waves of the epidemic in Milan, Italy: A prospective observational study.

ABSTRACT:

Introduction

This paper describes how mortality among hospitalised COVID-19 patients changed during the first three waves of the epidemic in Italy.

Methods

This prospective cohort study used the Kaplan-Meier method to analyse the time-dependent probability of death of all of the patients admitted to a COVID-19 referral centre in Milan, Italy, during the three consecutive periods of: 21 February-31 July 2020 (first wave, W1), 1 August 2020-31 January 2021 (second wave, W2), and 1 February-30 April 2021 (third wave, W3). Cox models were used to examine the association between death and the period of admission after adjusting for age, biological sex, the time from symptom onset to admission, disease severity upon admission, obesity, and the comorbidity burden.

Results

Of

SUBMITTER: Giacomelli A 

PROVIDER: S-EPMC9000097 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature