Selective Formation of Intramolecular Hydrogen-Bonding Palladium(II) Complexes with Nucleosides Using Unsymmetrical Tridentate Ligands.

ABSTRACT: Three palladium(II) complexes with amino-amidato-phenolato-type tridentate ligands were synthesized and characterized by ¹H NMR spectroscopy and X-ray crystallography. The strategic arrangement of a hydrogen-bond donor and acceptor adjacent to the substitution site of the Pd^II complex allowed the selective coordination of nucleosides. Among two pyrimidine-nucleosides, cytidine and 5-methyluridine, cytidine was successfully coordinated to the Pd^II complex while 5-methyluridne was not. On the other hand, both purine-nucleosides, adenosine and guanosine, were coordinated to the Pd^II complex. As purines have several coordination sites, adenosine afforded three kinds of coordination isomers expected from the three different donors. However, guanosine

SUBMITTER: Mitsuhashi R 

PROVIDER: S-EPMC9000330 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature