β-Adrenergic blockade in patients with dementia and hip fracture is associated with decreased postoperative mortality.

ABSTRACT:

Purpose

Dementia, present in 20% of hip fracture patients, is associated with an almost threefold increase in postoperative mortality risk. These patients have a substantially higher incidence of cardiovascular, respiratory, and cerebrovascular mortality after hip fracture surgery compared to patients without dementia. This study aimed to investigate the association between beta-blocker therapy and postoperative mortality in patients with dementia undergoing hip fracture surgery.

Methods

This nationwide study included all patients in Sweden with the diagnosis of dementia who underwent emergency surgery for a hip fracture between January 2008 and December 2017. Cases where the hip fracture was pathological or conservatively managed were not included. Poisson regression analys

SUBMITTER: Ioannidis I 

PROVIDER: S-EPMC9001220 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature