PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study.

ABSTRACT:

Background

A recently developed haemostatic peptide gel for endoscopic application has been introduced to improve the management of gastrointestinal bleeding. The aim of this pilot study was to evaluate the feasibility, safety, efficacy and indication profiles of PuraStat in a clinical setting.

Methods

In this prospective observational multicentre pilot study, patients with acute non-variceal gastrointestinal bleeding (upper and lower) were included. Primary and secondary application of PuraStat was evaluated. Haemoglobin, prothrombin time, platelets and transfusion behaviour were documented before and after haemostasis. The efficacy of PuraStat was assessed during the procedure, at 3 days and 1 week after application.

Results

111 patients with acute gastrointestinal

SUBMITTER: Branchi F 

PROVIDER: S-EPMC9001238 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature