Severe but reversible impaired diaphragm function in septic mechanically ventilated patients.

ABSTRACT:

Background

Whether sepsis-associated diaphragm dysfunction may improve despite the exposure of mechanical ventilation in critically ill patients is unclear. This study aims at describing the diaphragm function time course of septic and non-septic mechanically ventilated patients.

Methods

Secondary analysis of two prospective observational studies of mechanically ventilated patients in whom diaphragm function was assessed twice: within the 24 h after intubation and when patients were switched to pressure support mode, by measuring the endotracheal pressure in response to bilateral anterior magnetic phrenic nerve stimulation (Ptr,stim). Change in diaphragm function was expressed as the difference between Ptr,stim measured under pressure support mode and Ptr,stim measured withi

SUBMITTER: Lecronier M 

PROVIDER: S-EPMC9001790 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature