Non-erythropoiesis-stimulating agent, non-iron therapies for the management of anaemia: protocol for a scoping review.

ABSTRACT:

Introduction

Preoperative anaemia is associated with poor postoperative outcomes and is the strongest predictor of allogenic blood transfusion, which contributes further to patient morbidity. Emphasis has been placed on correcting anaemia prior to surgery to mitigate these outcomes. Conflicting evidence exists regarding the benefit of currently recommended interventions. With greater understanding of iron haemostasis and erythropoiesis, novel therapies have been identified. These are at varying stages of development with some demonstrating promising results in patients with chronic kidney disease. It is not known how these agents have been studied outside this population, particularly in the perioperative context. To address this, we will conduct a scoping review of the published l

SUBMITTER: Devlin P 

PROVIDER: S-EPMC9003621 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature