Comparison of Clinical and Imaging Outcomes of Different Doses of Adipose-Derived Stromal Vascular Fraction Cell Treatment for Knee Osteoarthritis.

ABSTRACT: Favorable clinical outcomes of intra-articular injection of adipose-derived stromal vascular fraction (SVF) cells for knee osteoarthritis (OA) have been reported, but the effects of different doses of SVF cells have not been examined. This study aimed to compare the short-term clinical and imaging outcomes of different doses of SVF cells for knee OA treatment. This study included 60 patients with knee OA who underwent intra-articular injection of SVF cells. The follow-up period was at least 12 months. Thirty patients received an intra-articular injection of 2.5×10⁷ SVF cells (low-dose group), and the remaining 30 patients received an intra-articular injection of 5.0×10⁷ SVF cells (high-dose group). Clinical evaluations were performed for the Knee injury and Osteoarthr

SUBMITTER: Tsubosaka M 

PROVIDER: S-EPMC9003644 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature