Surgery improves survival in bladder signet-ring cell carcinoma-a population-based study.

ABSTRACT:

Objectives

The purpose of this study is to determine the therapeutic value of surgery in individuals with urinary bladder signet ring cell carcinoma (SRCC). Surgery has not been examined as a prognostic factor for urinary bladder cancer (SRCC).

Materials and methods

Using the Surveillance, Epidemiology, and End Results program (SEER), patients with urinary bladder SRCC who presented from 1975 to 2018 were included in a retrospective study. The effect of surgical therapy on cause-specific survival (CSS) and overall survival (OS) was examined using univariate and multivariate Cox regression models. We subdivided 595 patients with SRCC into 2 groups, as follows: 496 who underwent surgery; and 99 who did not undergo surgery.

Results

Males had high predominance in all case

SUBMITTER: Alradhi M 

PROVIDER: S-EPMC9003658 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature