Impact of habitual sedentary patterns on popliteal artery endothelial-dependent vasodilation in healthy adults.

ABSTRACT:

Introduction

Acute, laboratory-based bouts of prolonged sitting attenuate lower-limb arterial endothelial-dependent vasodilation. However, the impact of habitual sedentary patterns on popliteal artery endothelial health is unclear. We tested the hypothesis that greater habitual total sedentary time, more time spent in prolonged sedentary bouts, and fewer sedentary breaks would be associated with worse popliteal flow-mediated dilation (FMD) responses.

Methods

This cross-sectional study used 98 healthy participants (19-77 years, 53 females) that wore an activPAL monitor on the thigh for 6.4 ± 0.8 days to objectively measure sedentary activity and completed a popliteal ultrasound assessment to determine FMD. Both relative (%baseline diameter) and absolute (mm) FMD were calculat

SUBMITTER: Shivgulam ME 

PROVIDER: S-EPMC9003777 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature