The associations between interleukin-17 single-nucleotide polymorphism and colorectal cancer susceptibility: a systematic review and meta-analysis.

ABSTRACT:

Background

Numerous case-control studies have reported associations between interleukin-17 (IL-17) polymorphisms and colorectal cancer; however, the results were inconsistent. The aim of this meta-analysis was to further clarify the effects of IL-17 polymorphisms on colorectal cancer susceptibility.

Materials and method

Relevant studies were extracted from the electronic databases PubMed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), and the Chinese Biomedical Literature Database (CMB) up to April 2021. The odds ratio and 95% confidence interval were used to estimate the strength of the associations.

Results

Ten articles including 2599 cases and 2845 controls were enrolled in our research after strict literature screening. Highly significant

SUBMITTER: Li G 

PROVIDER: S-EPMC9004118 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature