TE Density: a tool to investigate the biology of transposable elements.

ABSTRACT:

Background

Transposable elements (TEs) are powerful creators of genotypic and phenotypic diversity due to their inherent mutagenic capabilities and in this way they serve as a deep reservoir of sequences for genomic variation. As agents of genetic disruption, a TE's potential to impact phenotype is partially a factor of its location in the genome. Previous research has shown TEs' ability to impact the expression of neighboring genes, however our understanding of this trend is hampered by the exceptional amount of diversity in the TE world, and a lack of publicly available computational methods that quantify the presence of TEs relative to genes.

Results

Here, we have developed a tool to more easily quantify TE presence relative to genes through the use of only a gene and TE

SUBMITTER: Teresi SJ 

PROVIDER: S-EPMC9004194 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature