Stem signatures associating SOX2 antibody helps to define diagnosis and prognosis prediction with esophageal cancer.

ABSTRACT:

Background

esophageal cancer is one of the deadliest diseases worldwide. Due to the ineffectual screening methods referring to early diagnosis, most people have lost their chance of radical resection when diagnosed with esophageal cancer. This aim of this study was designed to evaluate the latent values of the stem signatures-associated autoantibodies (AABS) in predicting the early diagnosis, and particularly seeking the precise predictive outcomes with sensitive SOX2. We also studied the potential immunotherapeutic targets and prospective long-term prognosis predicators of esophageal cancer.

Methods

The serum concentrations of selective antibodies were quantitated by enzyme-linked immunosorbent assay (ELISA), and a total of 203 local cases were enrolled. The TCGA databases

SUBMITTER: Peng ZY 

PROVIDER: S-EPMC9004505 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature