Serological testing for SARS-CoV-2 antibodies of employees shows low transmission working in a cancer center.

ABSTRACT:

Background

The COVID-19 pandemic led to emergency measures to continue patient care and research at a comprehensive cancer center while protecting both employees and patients. Determining exposure and infection rates with SARS-CoV-2 were important to adjust workplace policies over time.

Methods

Dana-Farber Cancer Institute (DFCI) has over 7,000 employees. Participation was voluntary. After consent, participants completed questionnaire of demographics, exposures and risk factors for COVID-19 illness at each time point (baseline, 3, 6, and 12 months) along with blood draws for SARS-CoV-2 antibody testing. Primary measure was determination of titers of SARS-CoV-2 spike protein IgG over time.

Results

In total, 745 employees enrolled from May 2020 to February 2021 (mean [S

SUBMITTER: Meyerhardt JA 

PROVIDER: S-EPMC9004747 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature