Effects of Prone Position on Lung Recruitment and Ventilation-Perfusion Matching in Patients With COVID-19 Acute Respiratory Distress Syndrome: A Combined CT Scan/Electrical Impedance Tomography Study.

ABSTRACT:

Objectives

Prone positioning allows to improve oxygenation and decrease mortality rate in COVID-19-associated acute respiratory distress syndrome (C-ARDS). However, the mechanisms leading to these effects are not fully understood. The aim of this study is to assess the physiologic effects of pronation by the means of CT scan and electrical impedance tomography (EIT).

Design

Experimental, physiologic study.

Setting

Patients were enrolled from October 2020 to March 2021 in an Italian dedicated COVID-19 ICU.

Patients

Twenty-one intubated patients with moderate or severe C-ARDS.

Interventions

First, patients were transported to the CT scan facility, and image acquisition was performed in prone, then supine position. Back to the ICU, gas exchange, respiratory

SUBMITTER: Fossali T 

PROVIDER: S-EPMC9005091 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature