Treatment of Diabetic Macular Edema with Aflibercept and Micropulse Laser (DAM Study).

ABSTRACT:

Purpose

To investigate the safety and efficacy of micropulse (MP) macular laser in combination with intravitreal aflibercept for the treatment of center-involved diabetic macular edema (CI-DME).

Methods

A single-blind prospective randomized controlled pilot trial was performed. In total, 30 eyes of 30 patients with CI-DME and best corrected visual acuity (BCVA) between, and including, 20/30 and 20/400 were enrolled. Enrolled eyes were randomized to 2 groups. Group 1 received intravitreal aflibercept injections (IVT-AFL) with sham laser. Group 2 received IVT-AFL with MP laser. Both groups were followed every 4 weeks for 48 weeks and retreatment was performed on pro re nata basis according to preset criteria. The main outcome measure was the average number of intravitre

SUBMITTER: Koushan K 

PROVIDER: S-EPMC9005121 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature