Reverse vaccinology approach for multi-epitope centered vaccine design against delta variant of the SARS-CoV-2.

ABSTRACT: The ongoing COVID-19 outbreak, initially identified in Wuhan, China, has impacted people all over the globe and new variants of concern continue to threaten hundreds of thousands of people. The delta variant (first reported in India) is currently classified as one of the most contagious variants of SARS-CoV-2. It is estimated that the transmission rate of delta variant is 225% times faster than the alpha variant, and it is causing havoc worldwide (especially in the USA, UK, and South Asia). The mutations found in the spike protein of delta variant make it more infective than other variants in addition to ruining the global efficacy of available vaccines. In the current study, an in silico reverse vaccinology approach was applied for multi-epitope vaccine construction against the spike prot

SUBMITTER: Jalal K 

PROVIDER: S-EPMC9005162 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature