Diagnostic utility of antigen detection rapid diagnostic tests for Covid-19: a systematic review and meta-analysis.

ABSTRACT:

Background

The early detection of coronavirus disease (COVID-19) infection to improve disease management becomes the greatest challenge. Despite the high sensitivity of RT-PCR, not only it was reported that 20-67% of infected patients had false-negative results. Rapid diagnostic tests (RDTs) are widely used as a point-of-care test for SARS-CoV-2 detection in pharyngeal and blood specimens. It's more appealing since it's less time-consuming, doesn't seem to be as expensive, and doesn't need any specific training, but the poor sensitivity is the major limitation. Several reports indicated the rapid test of blood and pharyngeal samples has the same sensitivity as the RT-PCR, but some reports have lower sensitivity, especially in asymptomatic patients.

Methods

In the present sur

SUBMITTER: Ghasemi S 

PROVIDER: S-EPMC9005339 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature