Risk assessment tools for QT prolonging pharmacotherapy in older adults: a systematic review.

ABSTRACT:

Purpose

Many drugs are associated with the risk of QT prolongation and torsades de pointes (TdP), and different risk assessment tools (RATs) are developed to help clinicians to manage related risk. The aim of this systematic review was to summarize the evidence of different RATs for QT prolonging pharmacotherapy.

Methods

A systematic review was conducted using PubMed and Scopus databases. Studies concerning risk assessment tools for QT prolonging pharmacotherapy, including older adults, were included. Screening and selection of the studies, data extraction, and risk of bias assessment were undertaken.

Results

A total of 21 studies were included, involving different risk assessment tools. Most commonly used tools were risk scores (n = 9), computerized physician order e

SUBMITTER: Skullbacka S 

PROVIDER: S-EPMC9005415 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature