Development and validation of the Safe Sleep Calculator to assess risk of sudden unexpected death in infancy.

ABSTRACT: We describe the development and validation of a Sudden Unexpected Death in Infancy (SUDI) risk assessment clinical tool. An initial SUDI risk assessment algorithm was developed from an individual participant data meta-analysis of five international SIDS/SUDI case-control studies. The algorithm was translated into a clinical web tool called the Safe Sleep Calculator, which was tested at the routine infant 6-week check-up in primary care clinics in New Zealand. Evidence was gathered through mixed-methods research to inform the revision of the algorithm and the clinical tool. The revised algorithm performance was validated on a new contemporary New Zealand SUDI case-control study dataset and the pilot population data set. The area under the Receiver Operator Characteristic (ROC) curve is 0.89

SUBMITTER: McIntosh CG 

PROVIDER: S-EPMC9005526 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature