Determinants of venous return in steady-state physiology and asphyxia-induced circulatory shock and arrest: an experimental study.

ABSTRACT:

Background

Mean circulatory filling pressure (Pmcf) provides information on stressed volume and is crucial for maintaining venous return. This study investigated the Pmcf and other determinants of venous return in dysrhythmic and asphyxial circulatory shock and arrest.

Methods

Twenty Landrace/Large-White piglets were allocated into two groups of 10 animals each. In the dysrhythmic group, ventricular fibrillation was induced with a 9 V cadmium battery, while in the asphyxia group, cardiac arrest was induced by stopping and disconnecting the ventilator and clamping the tracheal tube at the end of exhalation. Mean circulatory filling pressure was calculated using the equilibrium mean right atrial pressure at 5-7.5 s after the onset of cardiac arrest and then every 10 s until 1 

SUBMITTER: Chalkias A 

PROVIDER: S-EPMC9005574 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature