Quantifying the Impact of Capacity Constraints in Economic Evaluations: An Application in Precision Medicine.

ABSTRACT:

Background

Examples of precision medicine are complex interventions featuring both testing and treatment components. Because of this complexity, there are often barriers to the introduction of such interventions. Few economic evaluations attempt to determine the impact of these barriers on the cost-effectiveness of the intervention. This study presents a case study economic evaluation that illustrates how the value of implementation methods may be used to quantify the impact of capacity constraints in a decision-analytic model.

Methods

A baseline decision-analytic model-based economic evaluation of ALK mutation testing was reproduced from a published technology appraisal. Three constraints (commissioning awareness, localization of testing, and pathology laboratory cap

SUBMITTER: Wright SJ 

PROVIDER: S-EPMC9005833 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature