Incidental Findings on Low-Dose CT Scan Lung Cancer Screenings and Deaths From Respiratory Diseases.

ABSTRACT:

Background

Incidental respiratory disease-related findings are frequently observed on low-dose CT (LDCT) lung cancer screenings. This study analyzed data from the National Lung Screening Trial (NLST) to assess the relationship between such findings and respiratory disease mortality (RDM), excluding lung cancer.

Research question

Are incidental respiratory findings on LDCT scanning associated with increased RDM?

Study design and methods

Subjects in the NLST LDCT arm received three annual screens. Trial radiologists noted findings related to possible lung cancer, as well as respiratory-related incidental findings. Demographic characteristics, smoking history, and medical history were captured in a baseline questionnaire. Kaplan-Meier curves were used to assess cumulativ

SUBMITTER: Pinsky PF 

PROVIDER: S-EPMC9005861 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature